Folded Gastrulation, Cell Shape Change and the Control of Myosin Localization
A molecular study of how changes in cell shape are controlled in the fruit-fly embryo-drawing parallels to pathways involved in cancer metastasis and providing a complete chain of events from cell fate specification to physical changes in cell shape.--author supplied description
Faculty Start Year
Dawes - Hoang, R.E., Parmar * , K., Christiansen, A.E., Phelps,C., Brand, A., Wieschaus, E. F. folded gastrulation, cell shape change and the control of myosin localization (2005). Development 132 (18) 4165 - 4178 .