Submissions from 2005

HIM-8 binds to the X chromosome pairing center and mediates chromosome-specific meiotic synapsis, Carolyn M. Phillips, Chihunt Wong, Needhi Bhalla, and Philip M. Meneely

Quantitative atomic force microscopy image analysis of unusual filaments formed by the Acanthamoeba castellanii myosin II rod domain, Daniel J. Rigotti, Bashkim Kokona, Theresa Horne '03, Karl A. Johnson, Robert S. Manning, Suzanne Amador Kane, Walter Fox Smith, and Robert Fairman

Characterization of a molecular chaperone present in the eukaryotic flagellum, J. Shapiro, J. Ingram, and Karl A. Johnson


Towards the Development of Peptide Nanfilaments and Nanoropes as Smart Materials, Daniel E. Wagner '02, Charles L. Phillips '01, Wasif M. Ali '99, Grant E. Nybakken '99, Emily D. Crawford '02, Alexander D. Schwab, Walter Fox Smith, and Robert Fairman

Toward the development of peptide nanofilaments and nanoropes as smart materials, D. E. Wagner '02, C. L. Phillips '01, W. M. Ali '99, and Robert Fairman

CD44hi Memory-phenotype CD8 T Cells are responsible for persistent GVHD in vivo, Y. Zhang, G. Joe, E. Hexner, and Stephen G. Emerson

Post-Mitotic CD44lo CD8 T Cells in GVHD are Memory Stem Cells, Y. Zhang, G. Joe, E. Hexner, and Stephen G. Emerson

NF-Ya Activates Multiple Hematopoietic Stem Cell (HSC) Regulatory Genes and Promotes HSC Self-Renewal, J. Zhu, J. Zhang, G. Joe, and Stephen G. Emerson

Submissions from 2004


Rhodobacter capsulatus porphobilinogen synthase, a high activity metal ion independent hexamer, David W. Bollivar, Cheryl Clauson, Rachel Lighthall, and Robert Fairman

Protein dissection experiments reveal key differences in the equilibrium folding of alpha-lactalbumin and the calcium binding lysozymes, F. A. Chowdhury, Robert Fairman, Y. Bi, and Daniel J. Raleigh

Designer Stromal Cells for Hematopoietic Support versus Gene Therapy, Stephen G. Emerson

Releasing the Brake on Stem Cell Cycling: HSC Expansion by Inhibiting p21, Stephen G. Emerson

Remembering to Forget: Memory T Cells & GVHD, Stephen G. Emerson

Stem Cell Transplantation (Cord Blood Transplants), Stephen G. Emerson

Tanning before transplant: Lancing the Langherhans cell, Stephen G. Emerson

Temporal complexity within a translational control element in the nanos mRNA, Kevin M. Forrest, Ira E. Clark, Roshan A. Jain, and Elizabeth A. Gavis

DNA Breaks Promote Genomic Instability by Impeding Proper Chromosome Segregation, J. A. Kaye and Justine Melo

Graft-versus-leukemia in a retrovirally induced CML Model: Mechanisms of T Cell Killing, C. C. Matte, J. Cormier, B. E. Andersen, and Stephen G. Emerson

Antibiotic resistance of faecal Escherichia coli from healthy volunteers from eight developing countries, S. Nys, Iruka N. Okeke, S. Kariuki, and G. J. Dinant

Molecular epidemiology of the iron utilization genes of enteroaggregative Escherichia coli, Iruka N. Okeke, I. C. A. Scaletsky, E. H. Soars, and L. R. Macfarlane

Short Interfering RNA (siRNA) Targeting the Lyn Kinase Induce Massive Apoptosis in Primary Drug Resistant Chronic Myelogenous Leukemia Cells: A New Paradigm for Treating Refractory Leukemias, A. Ptasznik, Y. Nakata, Stephen G. Emerson, and A. M. Gewirtz

Molecular Pathways Regulating the Self-Renewal of Hematopoietic Stem Cells, M. I. Stein, J. Zhu, and Stephen G. Emerson

Peptide models provide evidence for significant structure in the denatured state of a rapidly folding protein: The villin headpiece subdomain, Y. F. Tang, Daniel J. Rigotti, Robert Fairman, and Daniel J. Raleigh

Structure‐ activity relationships for polychlorinated biphenyl binding to the aryl hydrocarbon receptor in a Dolphin kidney cell line., Kristen E. Whalen, M. J. Carvan, E. V. Hestermann, and B. A. Jensen

Dendritic cell-activated CD44hiCD8+ memory T cells are defective in mediating acute graft-versus-host disease but retain graft-versus-leukemia activity, Y. Zhang, G. Joe, E. Hexner, and Stephen G. Emerson

A New Bone to Pick: The Role of Osteoblasts in the Bone Marrow Stem Cell Niche, J. Zhu and Stephen G. Emerson

Submissions from 2003

Control of tetrapyrrole biosynthesis by alternate quaternary forms of porphobilinogen synthase, S. Breinig, J. Kervinen, L. Stith, and Robert Fairman

Cutting Edge: Identification of the Targets of Clonal Deletion in an Unmanipulated Thymus, H. J. Cho, S. G. Edmondson, A. D. Miller, and Jennifer Punt

Early Progress in the Clinical Application of Hematopoietic Progenitor Cell Expansion? Current Status and Future Prospects, S. M. Devine, H. M. Lazarus, and Stephen G. Emerson

Molecular and cellular approaches to understanding the sensitivity of marine mammals to persistent organic pollutants., M. E. Hahn, B. A. Jensen, E-Y. Kim, and Kristen E. Whalen

Bringing Classical Embryology to C.elegans Gastrulation, Rachel E. Hoang, Jennifer A. Zallen, and Eric F. Wieschaus

The SNARE motif contributes to rbet1 intracellular targeting and dynamics independently of SNARE interactions, Ashwini P. Joglekar, Dalu Xu, Daniel J. Rigotti, and Robert Fairman

Axolotl pronephric duct migration requires an epidermally derived, laminin 1-containing extracellular matrix and the integrin receptor alpha 6 beta 1, Andrea R. Morris, J. Drawbridge, and M. S. Steinberg

Antibiotic Use and Resistance in Developing Countries, Iruka N. Okeke

Export of antimicrobial drugs by West African travelers, Iruka N. Okeke and A. Lamikanra

Etiology of acute diarrhea in adults in Southwestern Nigeria, Iruka N. Okeke, A. Ojo, A. Lamikanra, and J. B. Kaper

Antibiotic Resistance in Africa - Discerning the Enemy, Plotting a Defense, Iruka N. Okeke and A. Sosa

Mechanism of XIAP-mediated inhibition of caspase-9, E. N. Shiozaki, J. Chai, D. J. Rigotti, and Robert Fairman

NF-Ya,b,c Interacts with USF1/2 to Activate the HOXB4 Promoter in Human Hematopoietic Cells and Repress Granulopoiesis, J. Zhu, D. Giannola, Y. Zhang, and Stephen G. Emerson

Submissions from 2002

An Invitation to T and More: Notch Signaling in Lymphopoiesis, D. Allman, Jennifer Punt, D. J. Izon, and W. S. Pear

Hematopoiesis and the Hematopoietic Growth Factors, Stephen G. Emerson

Characterization of large peptide fragments derived from the N-terminal domain of the ribosomal protein L9: Definition of the minimum folding motif and characterization of local electrostatic interactions, Jia-Cherng Horng, Viktor Moroz, Daniel J. Rigotti, and Robert Fairman

Deciphering the role of Notch signaling in lymphopoiesis, D. J. Izon, Jennifer Punt, and W. S. Pear

Coupling of ligand binding and dimerization of helix-loop-helix peptides: Spectroscopic and sedimentation analyses of calbindin D9k EF-hands, Karin Julenius, Eva Thulin, James Robblee '98, and Robert Fairman

Crossover distribution and high interference for both the X chromosome and an autosome during oogenesis and spermatogenesis in Caenorhabditis elegans, Philip M. Meneely, A. F. Farago '00, and T. M. Kauffman '99

Vibrio cholerae, Iruka N. Okeke, J. Eardley, C. C. Bailey, and J. B. Kaper

Antibiotic-resistant cell-detaching Escherichia coli strains from Nigerian children, Iruka N. Okeke, H. Steinruck, K. J. Kanack, and S. J. Elliot

Exploring the role of alanine in the structure of the Lac repressor tetramerization domain, a ferritin-like ala-coil, Amy Solan '99, Kiira Ratia '99, and Robert Fairman

Regulation of intracellular pH in human melanoma: potential therapeutic implications, M. L. Wahl, Judith A. Owen, R. Burd, and R. A. Herlands '01


Preterminal host dendritic cells in irradiated mice prime CD8+ T cell–mediated acute graft-versus-host disease, Yi Zhang, Jean-Pierre Louboutin, Jiang Zhu, and Stephen G. Emerson

APCs in the liver and spleen recruit activated allogeneic CD8(+) T cells to elicit hepatic graft-versus-host disease, Y. Zhang, Warren D. Shlomchik, Gerard Joe, and Stephen G. Emerson

Hematopoietic Cytokines, Transcription Factors and Lineage Commitment, J. Zhu and Stephen G. Emerson

Submissions from 2001


Separation of Notch1 promoted lineage commitment and expansion/transformation in developing T cells, David M. Allman, Fredrick G. Karnell, Jennifer Punt, and Sonia Bakkour

Hybrid HIV/MSCV LTR enhances transgene expression of lentiviral vectors in human CD34+ hematopoietic cells, J. K. Choi, N. Hoang, A. M. Vilardi, and Stephen G. Emerson

Comparative study of peptide models of the alpha-domain of alpha-lactalbumin, lysozyme, and alpha-lactalbumin/lysozyme chimeras allows the elucidation of critical factors that contribute to the ability to form stable partially folded states, S. J. Demarest, S. Q. Zhou, J. Robblee, and Robert Fairman

Punching Holes in GVHD, Stephen G. Emerson

Marrow Stem Cell Transplantation for Fibrodysplasia Ossificans Progressiva (FOP): Has the Hour Arrived, Stephen G. Emerson and F. S. Kaplan

The Role Of Osteoblasts in Hematopoietic Stem Cell Biology, Stephen G. Emerson, R. S. Taichman, and S. Adams

Cell and Developmental Biology: A Shared Past, and Intertwined Future, Rachel E. Hoang and Eric F. Wieschaus

Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength, D. Izon, Jennifer Punt, F. Karnell, and L. W. Xu

Platelet-derived microparticles (PMPs) bind to hematopoietic stem/progenitor cells (HMPC) and enhance their engraftment, A. Janowsk-Wieczorek, M. Jajka, J. Kijowki, and Stephen G. Emerson

, Multiple defensive roles for triterpene glycosides from two Caribbean sponges., J. Kubanek, Kristen E. Whalen, S. Engel, and S. Kelly

Selective T cell Subset Ablation Demonstrates a Role for T1 and T2 Cells in Ongoing Acute Graft versus Host Disease: A Model System for the Reversal of Disease, J. Liu, B. E. Anderson, M. E. Robert, and Stephen G. Emerson

Structure and Function of Factor XIII, Ariel G. Loewy

Cell surface-directed interaction of anthracyclines leads to cytotoxicity and nuclear factor kappaB activation but not apoptosis signaling., N. Maestre, Thomas R. Tritton, G. Laurent, and J. P. Jaffrezou

Numerous growth factors, cytokines, and chemokines are secreted by human CD34+ cells, myeloblasts, erythroblasts and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner, M. Majka, A. Janowsk-Wieczorek, J. Rataczak, and Stephen G. Emerson

Universal eigenvector statistics in a quantum scattering ensemble., B. Mehlig and Melvin Santer

espC pathogenicity island of enteropathogenic Escherichia coli encodes an enterotoxin, J. L. Mellies, F. Navarro-Garcia, Iruka N. Okeke, and J. Frederickson


Two Checkpoint Complexes Are Independently Recruited to Sites of DNA Damage in vivo, Justine Melo

Platelet glycoprotein V binds to collagen and participates in platelet adhesion and aggregation., S. Moog, P. Mangin, N. Lenain, and Melvin Santer

Differential requirement for SLP-76 domains in T cell development and function, P. S. Myung, G. S. Derimanov, M. S. Jordan, and Jennifer Punt

Microbiological investigation of an outbreak of acute gastroenteritis in Niger State, Nigeria, Iruka N. Okeke, A. B. Abudu, and A. Lamikanra

Comparative sequence analysis of the plasmid-encoded regulator of enteropathogenic Escherichia coli Strains, Iruka N. Okeke, J. A. Borneman, S. Shin, and J. L. Mellies

Dissemination of antibiotic-resistant bacteria across geographic borders, Iruka N. Okeke and E. Edelman

Bacteriological quality of skin-moisturizing creams and lotions distributed in a tropical developing country, Iruka N. Okeke and A. Lamikanra

Enteroaggregative Escherichia coli, Iruka N. Okeke and J. P. Nataro

Quantitative analysis of DNA binding by the Escherichia coli arginine repressor, D. Szwajkajzer, L. H. Dai, J. W. Fukayama, and Robert Fairman

Hepatocyte Growth Factor is secreted by osteoblasts and constitutively supports hematopoiesis, R. S. Taichman, K. Ehrenman, J. Reilly, and Stephen G. Emerson

Integrated learning: passing fad or foundation for the future?, Thomas R. Tritton

Effects of charged amino acids at b and c heptad positions on specificity and stability of four-chain coiled coils, Colynda Vu '99, James Robblee '98, Karin M. Werner '99, and Robert Fairman

Formation of a stable hetero-dimer between Smad2 and Smad4, J. W. Wu, Robert Fairman, J. Penry, and Y. Shi

Crystal structure of a phosphorylated Smad2: recognition of phosphoserine by the MH2 domain and insights on Smad function in TGA-beta signaling, J. W. Wu, M. Hu, J. J. Chai, and Robert Fairman

Submissions from 2000

The ETK2 Receptor Tyrosine Kinase Promotes the Survival of Growth Factor-Dependent FDC-P1 Progenitor Cells, C. Darby, D. Giannola, and Stephen G. Emerson

Immature CD4+CD8+ do not polarize lipid rafts in response to TCR-mediated costimulation, Peter J. R. Ebert '00, Josh F. Baker '01, and Jennifer Punt

The Hematopoietic Microenvironment, Stephen G. Emerson, S. Adams, and R. S. Taichman

Axonemal dynein at the Hybrid Sterility 6 locus: implications for t haplotype-specific male sterility and the evolution of species barriers, J. Fossella, S. A. Samant, L. M. Silver, and Karl A. Johnson


Hematopoietic expression of HOXB4 is regulated in normal and leukemic stem cells through transcriptional activation of the HOXB4 promoter by USF-1 and USF-2, D. Giannola, W. D. Shlomchik, M. Jeganthesan, and Stephen G. Emerson

Structural analysis of the neuronal SNARE protein syntaxin-1A, J. C. Lerman, James Robblee '98, Robert Fairman, and F. M. Hughson

Local interactions and the role of the 6-120 disulfide bond in alpha-lactalbumin: implications for formation of the molten globule state, D. F. Moriarty, S. J. Demarest, James Robblee '98, and Robert Fairman

Antibiotic resistance in Escherichia coli from Nigerian students, 1986 1998, Iruka N. Okeke, S. T. Fayinka, and A. Lamikanra

Heterogeneous virulence of enteroaggregative Escherichia coli strains isolated from children in Southwest Nigeria, Iruka N. Okeke, A. Lamikanra, J. Czeczulin, and F. Dubovsky

Characterization of Escherichia coli strains from cases of childhood diarrhea in provincial southwestern Nigeria, Iruka N. Okeke, A. Lamikanra, H. Steinruck, and J. B. Kaper

A Tissue of T Cells, D. L. Porter and Stephen G. Emerson

Opportunistic screening for chlamydia infection in general practice: can we reach young women?, Melvin Santer, P. Warner, S. Wyke, and S. Sutherland

Rational modification of protein stability by the mutation of charged surface residues, S. Spector, M. Wang, S. A. Carp, and Robert Fairman

The Hematopoietic Microenvironment: Osteoblasts and the Hematopoietic Microenvironment, R. S. Taichman, M. J. Reilly, and Stephen G. Emerson

Disparity in the kinetics of onset of hypermutation in immunoglobulin heavy and light chains, H. van der Keyl, Ziad F. Gellad '97, and Judith A. Owen

Submissions from 1999

Analysis of transglutaminase-catalyzed isopeptide bonds in paired helical filaments and neurofibrillary tangles from Alzheimer's disease, B. J. Balin, Ariel G. Loewy, and D. M. Appelt

Positive selection as a developmental progression initiated by alpha beta TCR signals that fix TCR specificity prior to lineage commitment, A. Bhandoola, R. Cibotti, Jennifer Punt, and L. Granger

Collateral methotrexate resistance in cisplatin-selected murine leukemia cells, A. Bhushan, M. P. Hacker, and Thomas R. Tritton