A Pathoadaptive Deletion in an Enteroaggregative Escherichia coli Outbreak Strain Enhances Virulence in a Caenorhabditis elegans Model
Infection and Immunity
Research paper describing for the first time, a nematode model for enteroaggregative E. coli. The paper also reports that an outbreak strain of enteroaggregative E. coli has a pathoadaptive mutation, providing the first explanation for why this strain caused the largest enteroaggregative outbreak to date. --author-supplied description
Hwang, J, Mattei, LM, VanArendonk, LG, Meneely, PM and Okeke IN. (2010) A pathoadaptive deletion in an enteroaggregative Escherichia coli outbreak strain enhances virulence in a Caenorhabditis elegans model. Infection and Immunity, 78(9):4068-76.