A Pathoadaptive Deletion in an Enteroaggregative Escherichia coli Outbreak Strain Enhances Virulence in a Caenorhabditis elegans Model

Jennifer Hwang '09, Class of 2009, Haverford College
Lisa M. Mattei
Laura G. Van Arendonk '10, Class of 2010, Haverford College
Iruka N. Okeke, Haverford College


Research paper describing for the first time, a nematode model for enteroaggregative E. coli. The paper also reports that an outbreak strain of enteroaggregative E. coli has a pathoadaptive mutation, providing the first explanation for why this strain caused the largest enteroaggregative outbreak to date. --author-supplied description