Submissions from 1997

Spectroscopic properties of Escherichia coli UDP-N-acetylenolpyruvylglucosamine reductase, Milton J. Axley, Robert Fairman, Joseph Yanchunas, and Joseph J. Villafranca

Surface molecules that drive T cell development in vitro in the absence of thymic epithelium and in the absence of lineage-specific signals, Ricardo Cibotti, Jennifer Punt, Krishna S. Dash, Susan O. Sharrow, and Alfred Singer

Approach to the Patient with Leukocytosis, Stephen G. Emerson

Cytokines in Ex-Vivo Stimulation of Blood Progenitor Cells, Stephen G. Emerson

Heteronuclear (1H, 13C, 15N) NMR assignments and secondary structure of the basic region-helix-loop-helix domain of E47, Robert Fairman, Rita K. Beran-Steed, and T. M. Handel

Calcium binding peptides from alpha-lactalbumin: implications for protein folding and stability, Brian Kuhlman, Judith A. Boice, Wen-Jin Wu, Robert Fairman, and Daniel P. Raleigh

Exceptionally stable helix from the ribosomal protein L9: implications for protein folding and stability, B. Kuhlman, H. Y. Yang, Judith A. Boice, and Robert Fairman

Synthesis and use of a substrate for the detection of isopeptidase activity, Ariel G. Loewy, James K. Blodgett, Francis Rose Blase, and Matthew H. May

Chromosomal signal for sex determination in Caenorhabditis elegans, Philip M. Meneely

A study of the effect of the urban/rural divide on the incidence of antibiotic resistance in Escherichia coli, Iruka N. Okeke and A. Lamikanra


T cell receptor (TCR)-induced death of immature CD4+CD8+ thymocytes by two distinct mechanisms differing in their requirement for CD28 costimulation: implications for negative selection in the thymus, Jennifer Punt, Wendy Havran, Ryo Abe, and Apurva Sarin

Protein designed by binary patterning of polar and nonpolar amino acids displays native-like properties, Sushmita Roy, Gayathri Ratnaswamy, Judith A. Boice, and Robert Fairman

Screening for genital chlamydial infection in women in general practice. Psychological effects of such screening are important, Melvin Santer

Infection and replication of human cytomegalovirus in bone marrow stromal cells: Effects on the production of IL-6, MIP-1alpha, and TGF-beta1, Russell S. Taichman, M. R. Nassiri, M. J. Reilly, and Stephen G. Emerson

Human osteosarcomas inhibit hematopoietic colony formation: Partial reversal by antibody to transforming growth factor-beta 1, Russell S. Taichman, M. J. Reilly, and Stephen G. Emerson

CD34+ bone marrow cells induce the expression and secretion of interleukin 6 (IL-6) by normal human osteoblasts, Russell S. Taichman, M. J. Reilly, R. S. Verma, and Stephen G. Emerson

Incomplete endoplasmic reticulum (ER) retention in immature thymocytes as revealed by surface expression of ""ER-resident"" molecular chaperones, David L. Wiest, Avinash Bhandoola, Jennifer Punt, Gert Kreibich, David McKean, and Alfred Singer

Developmentally regulated expression of peanut agglutinin (PNA)-specific glycans on murine thymocytes, Wenyu Wu, Jennifer Punt, Larry C. Granger, and Susan O. Sharrow

Submissions from 1996

Correlation of altered tyrosine phosphorylation with methotrexate resistance in a cisplatin-resistant subline of L1210 cells, Alok Bhushan, Diana Wroblewski, Yongzhi Xuan, Thomas R. Tritton, and Miles P. Hacker

Thermodynamic analysis of a designed three-stranded coiled coil, Judith A. Boice, Gregg R. Dieckmann, William F. DeGrado, and Robert Fairman

Structural characterization of the tumor suppressor p16, an ankyrin-like repeat protein, Judith A. Boice and Robert Fairman

Tamoxifen induces TGF-beta 1 activity and apoptosis of human MCF-7 breast cancer cells in vitro, Hongmin Chen, Thomas R. Tritton, Nicholas Kenny, and Marlene Absher

Ex-Vivo Expansion of Hematopoietic Precursors, Progenitors, and Stem Cells: The Next Generation of Cellular Therapeutics, Stephen G. Emerson

The Potential for Clinical Ex Vivo Hematopoiesis, Stephen G. Emerson

Design of heterotetrameric coiled coils: evidence for increased stabilization by Glu(-)-Lys(+) ion pair interactions, Robert Fairman, Hann-Guang Chao, Thomas B. Lavoie, and Joseph J. Villafranca

Diversification of arthropod Hox genes as a paradigm for the evolution of gene functions, Rachel E. Hoang

Structural studies of Escherichia coli UDP-N-acetylmuramate: L-alanine ligase, H. Jin, J. J. Emanuele Jr., Robert Fairman, and J. G. Robertson

DPY-26, a Link between Dosage Compensation and Meiotic Chromosome Segregation in the Nematode, Jason D. Lieb, Elizabeth E. Capowski, Philip M. Meneely, and Barbara J. Meyer

Primary structure of a cytosolic malate dehydrogenase of the amitochondriate eukaryote, Trichomonas vaginalis, A. Markos, Andrea R. Morris, C. Rozario, and M. Muller

Identification of Sex-specific Quantitative Trait Loci Controlling Alcohol Preference in C57BL/6 mice, Justine Melo

Comparison of benzimidazole nucleosides and ganciclovir on the in vitro proliferation and colony formation of human bone marrow progenitor cells, M. Reza Nassiri, Stephen G. Emerson, Rodrigo V. Devivar, Leroy B. Townsend, and John C. Drach

Successful in vitro antigen-dependent activation of 24-hour-old peripheral blood lymphocytes, Judith A. Owen, K. Muirhead, C. Jensen, and Z. L. Jonak


Lineage commitment in the thymus: only the most differentiated (TCRhibcl-2hi) subset of CD4+CD8+ thymocytes has selectively terminated CD4 or CD8 synthesis, Jennifer Punt, Harumi Suzuki, Larry C. Granger, and Susan O. Sharrow

The Immune Response to Leukemias. Acta Haematologica, Warren Shlomchik and Stephen G. Emerson

Human MG-63 and SaOS-2 osteosarcoma cell lines produce G-CSF and GM-CSF: Identification and partial characterization of cell-associated isoforms, Russell S. Taichman and Stephen G. Emerson

Human osteoblasts support human hematopoietic progenitor cells in long term in vitro bone marrow cultures, Russell S. Taichman, M. J. Reilly, and Stephen G. Emerson

Gene family use and somatic mutation in primary and secondary fluorescein-specific IgM antibody responses, H. van der Keyl, C. Hsu, A. Tolat, and Judith A. Owen

Investigations on the mechanisms of methotrexate resistance in a cisplatin-resistant L1210 murine leukemia cell subline, Diana Wroblewski, Alok Bhushan, Yongzhi Xuan, and Thomas R. Tritton


Identification of CD8 as a peanut agglutinin (PNA) receptor molecule on immature thymocytes, Wenyu Wu, Patricia H. Harley, Jennifer Punt, and Susan O. Sharrow

Asbestos causes stimulation of the extracellular signal-regulated kinase 1 mitogen-activated protein kinase cascade after phosphorylation of the epidermal growth factor receptor, C. L. Zanella, J. Posada, Thomas R. Tritton, and B. T. Mossman

Submissions from 1995

The evolving role of Hox genes in arthropods, Michael Akam, Michelis Averof, Rachel E. Hoang, and Jaime Castelli-Gair

Dax, a locust Hox gene related to fushi-tarazu but showing no pair-rule expression, Michael Akam, Iain Dawson, Rachel E. Hoang, and Jaime Castelli-Gair

Design of two-stranded and three-stranded coiled-coil peptides, Stephen Betz, Robert Fairman, Karyn O'Neil, James D. Lear, and William Degrado

Identification of alternative exons, including a novel exon, in the tyrosine kinase receptor gene Etk2/tyro3 that explain differences in 5' cDNA sequences, Leslie G. Biesecker, Diane Giannola, and Stephen G. Emerson

Identification of a molecular chaperone in the eukaryotic flagellum and its localization to the site of microtubule assembly, M. A. Bloch and Karl A. Johnson

IL-1 alpha upregulates TNF alpha receptors expressed by a clonally derived bone marrow stromal cell strain: Implications for cytokine redundancy and synergy, Jerry Caldwell and Stephen G. Emerson


Retroviral-mediated gene transfer in human bone marrow cells growth in continuous perfusion culture vessels, Peter G. Eipers, John C. Krause, Barnhard O. Palsson, and Stephen G. Emerson

In Vitro Expansion of Hematopoietic Cells for Clinical Application, Stephen G. Emerson, Barnhard O. Palsson, Michael F. Clarke, and Samuel M. Silver

Characterization of a new four-chain coiled-coil: influence of chain length on stability, Robert Fairman, Hann-Guang Chao, Luciano Mueller, and Thomas B. Lavoie

Identification of Kv1.1 expression by murine CD4-CD8- thymocytes. A role for voltage-dependent K+ channels in murine thymocyte development, Bruce D. Freedman, B. K. Fleischmann, Jennifer Punt, and G. Gaulton

DNA-binding domain of the hexameric arginine repressor, R. Grandori, T. A. Lavoie, M. Pflumm, and Robert Fairman

Fine specificity analysis indicates that the primary and secondary fluorescein-specific cytotoxic T cell receptor repertoires are indistinguishable, E. A. Hughes, G. Kinnel, C. Wickerham, and Judith A. Owen

Immunoelectron microscopy, Karl A. Johnson

Keeping the beat: form meets function in the Chlamydomonas flagellum, Karl A. Johnson

New motilities and motors in the flagella of Chlamydomonas, Karl A. Johnson


Early molecular events induced by TCR signaling in immature CD4+ CD8+ thymocytes, Kelly P. Kearse, Yousuke Takahama, Jennifer Punt, and Susan O. Sharrow

Bacterial capsules: a simple method for demonstration under the light microscope, Iruka N. Okeke and A. Lamikanra

Quality and bioavailability of tetracycline capsules in a Nigerian semi-urban community, Iruka N. Okeke and A. Lamikanra

T cell development, Jennifer Punt and A. Singer

Ribosomal RNA: An Historical Perspective, Melvin Santer

A mutation at the universally conserved position 529 in Escherichia coli 16S rRNA creates a functional but highly error prone ribosome., U. V. Santer, Julie Cekleniak '93, Sukesh K. Kansil '94, and Melvin Santer

Expression of gamma-glutamyl transpeptidase in midgestation mouse yolk sac and mouse visceral yolk sac carcinoma cells, Antonia R. Sepulveda, Geetha M. Habib, Andrea Damjanov, and Slavica Smit Matacic

Markedly asymmetric requirements for commitment to the CD4+ vs. CD8+ T cell lineage, H. Suzuki, Jennifer Punt, Larry C. Granger, and A. Singer

Submissions from 1994

Meiotic mutants that cause a polar decrease in recombination on the X chromosome in Caenorhabditis elegans, Sherryl A. Broverman and Philip M. Meneely

IL-1 alpha and TNF alpha act synergistically to stimulate high level GM-CSF and G-CSF production from human bone marrow stromal cells and stromal cell strains, Jerry Caldwell and Stephen G. Emerson

Retroviral Gene Transfer into Human Hematopoietic Cells Using Rapidly Perfused Long Term Bone Marrow Culture, F. El-Awar, J. C. Krause, Barnhard O. Palsson, and Stephen G. Emerson

Hematopoietic Growth Factors, J. F. Farnen and Stephen G. Emerson

G-CSF Production and G-CSF Receptor Structure in Patients with Congenital Neutropenia, Susan C. Guba, Carolyn A. Sartor, Raymond Hutchinson, Laurence A. Boxer, and Stephen G. Emerson

Localization of a kinesin-related protein to the central pair apparatus of the Chlamydomonas reinhardtii flagellum, Karl A. Johnson, M. A. Haas, and J. L. Rosenbaum

Transition from TCR-b dimer to TCR-ab expressing cells by introduction of an a-chain in an immature thymocyte cell line, I. Kuwabara, H. Ohno, Jennifer Punt, and Y. Hashimoto

Sex determination in polyploids of Caenorhabditis elegans, Philip M. Meneely

Sex determination and dosage compensation: lessons from flies and worms, S. M. Parkhurst and Philip M. Meneely


Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28, Jennifer Punt, Barbara A. Osborne, Yousuke Takahama, and Susan O. Sharrow


Stoichiometry of the T cell antigen receptor complex: each TCR/CD3 complex contains one TCR alpha, one TCR beta, and two CD3 epsilon chains, Jennifer Punt, Joseph L. Roberts, Kelly P. Kearse, and Alfred Singer


Human osteoblasts support hematopoiesis through the production of granulocyte colony stimulating factor, Russell S. Taichman and Stephen G. Emerson

Expansion of hematopoietic progenitor cells from umbilical cord blood via continuous perfusion culture, G. Van Zant, I. Drubachevsky, S. Rummel, and Stephen G. Emerson

Submissions from 1993

(i, i + 4) Phe-His interaction studied in an alanine-based alpha-helix, Katherine M. Armstrong, Robert Fairman, and Robert L. Baldwin

Interleukin-6 is a component of human umbilical cord serum and stimulates hematopoiesis in embryonic stem cells in vitro, Leslie G. Biesecker and Stephen G. Emerson

Identification of four murine cDNAs encoding putative protein kinases from primitive embryonic stem cells differentiated in vitro, Leslie G. Biesecker, Lisa R. Gottschalk, and Stephen G. Emerson

The Role of Cytoadhesion in Human Stem Cell Differentiation, Jerry Caldwell, Barnhard O. Palsson, and Stephen G. Emerson

A randomized controlled phase III trial of recombinant human G-CSF in treatment of patients with severe chronic neutropenia, David C. Dale, Mary Ann Bonilla, Mark W. Davis, and Stephen G. Emerson

Anomalous expression of P-glycoprotein in highly drug-resistant human KB cells, Elizabeth D. Dolci, Robin Abramson, Yongzhi Xuan, and Thomas R. Tritton

Angioedema presenting as chronic gastroinitestinal symptoms, Stephen L. Eck, James H. Morse, David A. Janssen, Stephen G. Emerson, and David M. Markovitz

Multiple oligomeric states regulate the DNA binding of helix-loop-helix peptides, Robert Fairman, Rita K. Beran-Steed, Spencer J. Anthony-Cahill, and James D. Lear


Molecular regulation of the human IL-3 gene: Inducible T cell restricted expression requires intact AP-1 and Elf-1 nuclear protein binding sites, L. Gottschalk, D. Giannola, and Stephen G. Emerson

Unwinding dosage compensation, S. Henikoff and Philip M. Meneely

Flagellar regeneration in Chlamydomonas: A model system for studying organelle assembly , Karl A. Johnson and Joel L. Rosenbaum

Large-Scale Expansion of Human Hematopoietic Stem and Progenitor Cells from Bone Marrow Mononuclear Cells in Continuous Perfusion Culture, M. R. Koller, Stephen G. Emerson, and Barnhard O. Palsson

A motility in the eukaryotic flagellum unrelated to flagellar beating, K. G. Kozminski, Karl A. Johnson, and P. Forscher

Purification and characterization of a novel zinc-proteinase from cultures of Aeromonas hydrophila, Ariel G. Loewy, Ursula V. Santer, Maciej Wieczorek, James K. Blodgett, Steven W. Jones, and John C. Cheronis

Expansion of Human Bone Marrow Progenitor Cells in a Continuous Perfusion Hematopoietic Bioreactor, Barnhard O. Palsson, S. W. Paek, M. Palsson, and Stephen G. Emerson

CD4+/CD8- thymocytes dominate the fetal thymus treated with a combination of anti-TCR-beta and anti-CD4 antibodies, Jennifer Punt, M. Hosono, and Y. Hashimoto

Functional effects of a G to U base change at position 530 in a highly conserved loop of Escherichia coli 16S RNA, Melvin Santer, U. Santer, K. Nurse, and A. Bakin

Protection from adriamycin cytotoxicity in L1210 cells by brefeldin A, Paul J. Vichi and Thomas R. Tritton

Activity of two novel anthracene-9,10-diones against human leukemia cells containing intercalator-sensitive or -resistant forms of topoisomerase II, Leonard A. Zwelling, Janice Mayes, Elizabeth Altschuler, and Thomas R. Tritton

Submissions from 1992

More than one way to slice an egg, Michael Akam and Rachel E. Hoang

Biotinylated GM-CSF analogs: Effect of linkage chemistry on activity and binding, Timothy P. Angelotti, Michael F. Clarke, Marc A. Longino, and Stephen G. Emerson

Molecular characterization of helix-loop-helix peptides, Spencer J. Anthony-Cahill, Pamela A. Benfield, Robert Fairman, and Zelda R. Wasserman

Recombinant Human Granulocyte-Colony Stimulating Factor in the Treatment of Patients with Neutropenia, Laurence A. Boxer, Raymond J. Hutchinson, and Stephen G. Emerson

Helix-forming propensity of D-alanine in a right-handed alpha-helix, Robert Fairman, Spencer J. Anthony-Cahill, and William F. DeGrado