Submissions from 2020

The Education of Future Immunologists: Lessons from the Doherty Lab, Judith Owen


Active Learning and Technology Approaches for Teaching Immunology to Undergraduate Students, Sharon A. Stranford, Judith Owen, Frances Mercer, and Roberta R. Pollock

Submissions from 2019

Co-culture and biogeography of Prochlorococcus and SAR11, Jamie Becker, Shane L. Hogle, Kali Rosendo, and Sallie W. Chisholm


Colorimetric Assay Reports on Acyl Carrier Protein Interactions, Acheampong K. Koki '19, Bashkim Kokona, Gabriel Braun '19, Danielle Jacobsen '19, Karl A. Johnson, and Louise K. Charkoudian

Mercury speciation and retention in a salt marsh undergoing long-term fertilization, Carl Lamborg, Tracy Mincer, William Buchanan, and Kristen E. Whalen

Working with Worms: Caenorhabditis elegans as a Model Organism, Philip M. Meneely, Caroline L. Dahlberg '01, and Jacqueline K. Rose


Microbial communities in the nepheloid layers and hypoxic zones of the Canary Current upwelling system, Stefan Thiele, Andreas Basse, Jamie Becker, and Andre Lipski

Roles of singleton tryptophan motifs in COPI coat stability and vesicle tethering, Sophie Travis, Bashkim Kokona, Robert Fairman, and Frederick M. Hughson


Bacterial alkylquinolone signaling contributes to structuring microbial communities in the ocean, Kristen E. Whalen, Jamie W. Becker, Anna M. Schrecengost '18, Yongjie Gao '20, and Nicole Giannetti '18

Submissions from 2018


Drosophila Insulin receptor regulates the persistence of injury-induced nociceptive sensitization, Seol Hee Im, Atit A. Patel, Daniel N. Cox, and Michael J. Galko

A Forward Genetic Screen in Zebrafish Identifies the G-protein coupled receptor CaSR as a modulator of Sensorimotor Decision-making, Roshan A. Jain, Christina Szi '18, Amy Zamora '18, Keisuke Sawada '17, and Emilia Cobbs '17

Microbiological quality and antimicrobial resistance characterization of Salmonella spp. in fresh milk value chains in Ghana, Angela Parry-Hanson Kunadu, Mark Holmes, Eric L. Miller, and Andrew J. Grant


A Cyfip2-Dependent Excitatory Interneuron Pathway Establishes the Innate Startle Threshold, Kurt C. Marsden, Roshan A. Jain, Marc A. Wolman, Ben Miltenberg '17, and Alberto E. Pereda

Eavesdropping and crosstalk between secreted quorum sensing peptide signals that regulate bacteriocin production in Streptococcus pneumoniae, Eric L. Miller, Morten Kjos, Monica I. Abrudan, Ian S. Roberts, and Jan-Willem Veening

Aggregative Adherence and Intestinal Colonization by Enteroaggregative Escherichia coli Are Produced by Interactions among Multiple Surface Factors, Iruka N. Okeke, Laura V. Blanton, Lawrence T. Wang, Jennifer Hofmann, Joshua DuBow '11, Alexander Lafrance '16, Stephen Kwak '12, Levi Bowers '17, Mandara C. Levine '18, Charles O. Hale '17, and Philip Meneely


The chemical cue tetrabromopyrrole induces rapid cellular stress and mortality in phytoplankton, Kristen E. Whalen, Christopher Kirby, Russell M. Nicholson '18, and Mia O'Reilly '18

Submissions from 2017


Hominids adapted to metabolize ethanol long before human-directed fermentation, Mathew Carrigan


Twists And Turns In Protein Assembly, Robert Fairman

Uncovering Protein-Protein Interactions through a Team-based Undergraduate Biochemistry Course, Robert Fairman, D. L. Cookmeyer, S. E. Winesett, Bashkim Kokona, and Louise K. Charkoudian

Sedimentation Velocity Analysis with Fluorescence Detection of Mutant Huntingtin Exon 1 Aggregation in Drosophila melanogaster and Caenorhabditis elegans, Robert Fairman, Surin Kim '15, Victoria D'Acunto '17, Jay Garcia '16, Nabeel Akhtar '13, Susanna Hoffman '14, Seema Doshi '16, and Kathleen Ulrich '18

Genetics: Genes, genomes, and evolution, Kate Heston, Rachel E. Hoang, Philip M. Meneely, and Iruka N. Okeke


Pherotype Polymorphism in Streptococcus pneumoniae Has No Obvious Effects on Population Structure and Recombination, Eric L. Miller, Benjamin A. Evans, Omar E. Cornejo, Ian S. Roberts, and Daniel E. Rozen

Diminishing Returns on Intragenic Repeat Number Expansion in the Production of Signaling Peptides, David W. Rogers, Ellen McConnell, Eric L. Miller, and Duncan Greig

Submissions from 2016


Steady at the wheel: conservative sex and the benefits of bacterial transformation, Ole Herman Ambur, Jan Engelstädter, Pål J. Johnsen, Eric L. Miller, and Daniel E. Rozen


Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO, Hande Boyanci, Tayyab Shah, Amanda Hurley, and Robert Fairman

Studying polyglutamine aggregation in Caenorhabditis elegans using an analytical ultracentrifuge equipped with fluorescence detection, Robert Fairman, Lynn Richmond '13, Jay Garcia '16, and Kathleen Ulrich '14

Weak tradeoff between xylem safety and xylem-specific hydraulic efficiency across the world's woody plant species, Sean M. Gleason, Mark Westoby, Steven Jansen, and Radika Bhaskar


A Bacterial Quorum-Sensing Precursor Induces Mortality in the Marine Coccolithophore, Emiliania huxleyi, E. L. Harvey, R. W. Deering, D. C. Rowley, and Kristen E. Whalen

Estrogens Suppress a Behavioral Phenotype in Zebrafish Mutants of the Autism Risk Gene, CNTNAP2, Ellen J. Hoffman, Katherine J. Turner, Joseph M. Fernandez, and Roshan A. Jain


Expression of Streptococcus pneumoniae Bacteriocins Is Induced by Antibiotics via Regulatory Interplay with the Competence System, Morten Kjos, Eric L. Miller, Jelle Slager, Frank B. Lake, and Oliver Gericke

Probing the selectivity of beta-hydroxylation reactions in non-ribosomal peptide synthesis using analytical ultracentrifugation, Bashkim Kokona, Emily S. Winesett '16, A. Nikolai von Krusenstiern '15, Robert Fairman, and Louise K. Charkoudian

Was atmospheric CO2 capped at 1000 ppm over the past 300 million years?, Jennifer C. McElwain, Isabel P. Montañez, Joseph D. White, and Jonathan P. Wilson

Pick Your Poisson: An Educational Primer for Luria and Delbruck's Classic Paper, Philip M. Meneely


Diverse ecological strategies are encoded by Streptococcus pneumoniae bacteriocin-like peptides, Eric L. Miller, Monica I. Abrudan, Ian S. Roberts, and Daniel E. Rozen

Climate, p(CO2) and terrestrial carbon cycle linkages during late Palaeozoic glacial-interglacial cycles, Isabel P. Montanez, Jennifer C. McElwain, Christopher J. Poulsen, and Jonathan P. Wilson

Diarrhoeagenic Escherichia coli in mother-child Pairs in Ile-Ife, South Western Nigeria, Iruka N. Okeke, Babatunde W. Odetoyin, Jennifer Hofmann, and Aaron O. Aboderin

Asynchronous spore germination in isogenic natural isolates of Saccharomyces paradoxus, Rike B. Stelkens, Eric L. Miller, and Duncan Greig


Biosynthesis of coral settlement cue tertrabromopyrrole in marine bacteria by a uniquely adapted brominase-thiosterase enzyme pair., Kristen E. Whalen, Abrahim El Gamal, Vinayak Agarwal, and Stefan Diethelm

Hydraulics of Psilophyton and evolutionary trends in plant water transport after terrestrialization, Jonathan P. Wilson

Submissions from 2015


Socially mediated induction and suppression of antibiosis during bacterial coexistence, Monica I. Abrudan, Fokko Smakmann, Ard Jan Grimbergen, Sanne Westhoff, and Eric L. Miller


The interaction of Saccharomyces paradoxus with its natural competitors on oak bark, Vienna Kowallik, Eric L. Miller, and Duncan Greig

Effect of Helix Length on the Stability of the Lac Repressor Antiparallel Coiled Coil, Wheaton Little, James P. Robblee, Caroline L. Dahlberg, Bashkim Kokona, and Robert Fairman


Spore Germination Determines Yeast Inbreeding according to Fitness in the Local Environment, Eric L. Miller and Duncan Grieg

Enhancement of antibiotic activity against multidrug resistant bacteria by efflux pump inhibitor, 3,4‐dibromo‐2,5‐dione, isolated from a Pseudoalteromonas sp, Kristen E. Whalen, K. L. Poulson, R. W. Deering, and D. C. Rowley

A genome-wide screen identifies PAPP-AA-mediated IGFR signaling as a novel regulator of habituation learning, Marc A. Wolman, Roshan A. Jain, and Kurt C. Marsden

Submissions from 2014


Enteroaggregative Escherichia coli Have Evolved Independently as Distinct Complexes within the E-coli Population with Varying Ability to Cause Disease, Marie Anne Chattaway, Claire Jenkins, Dunstan Rajendram, and Iruka N. Okeke


Comparative Genomics of 274 Vibrio Cholerae Genomes Reveals Mobile Functions Structuring Three Niche Dimensions, Bas E. Dutilh, Cristiane C. Thompson, Ana C P Vicente, and Iruka N. Okeke


Mirror movement-like defects in startle behavior of zebrafish dcc mutants are caused by aberrant midline guidance of identified descending hindbrain neurons, Roshan A. Jain


Effect of Helical Flanking Sequences on the Morphology of Polyglutamine-Containing Fibrils, Bashkim Kokona, Karl A. Johnson, and Robert Fairman


Role of the Coiled-Coil Structural Motif in Polyglutamine Aggregation, Bashkim Kokona, Zachary P. Rosenthal, and Robert Fairman

Genetic Analysis: Genes, Genomes, and Networks in Eukaryotes, 2nd edition, Philip M. Meneely

Diagnostic Schemes for Reducing Epidemic Size of African Viral Hemorrhagic Fever Outbreaks, Iruka N. Okeke and Robert S. Manning

Confronting Contagion: Our Evolving Understanding of Disease, Melvin Santer


The effect of hybrid transgression on environmental tolerance in experimental yeast crosses, Rike B. Stelkens, M. A. Brockhurst, G. D.D. Hurst, Eric L. Miller, and Duncan Greig


Dissemination of the Transmissible Quinolone-Resistance Gene qnrS1 by IncX Plasmids in Nigeria, Eric T. Sumrall '13, Elizabeth B. Gallo '12, Aaron Aboderin Oladipo, Adebayo Lamikanra, and Iruka N. Okeke

Testing the Role of Charge and Structure on the Stability of Peptide-Porphyrin Complexes, James C. Taggart '13, Elizabeth Z. Welch, Mary F. Mulqueen, Vincent B. Dioguardi, and Robert Fairman

Submissions from 2013


The Carbon Isotope Organic Geochemistry of Early Ordovician Rocks from the Annascaul Formation, County Kerry, A. H. Jahren, Brian A. Schubert, Leszek Marynowski, and Jonathan P. Wilson


Using a Peptide System to test the Coiled-Coil Model of Polyglutamine Aggregation, Bashkim Kokona, Karl A. Johnson, and Robert Fairman


Flagellar Waveform Dynamics of Freely Swimming Algal Cells, H. Kurtuldu, D. Tam, A. E. Hosoi, and Karl A. Johnson


Cholera Outbreaks in Nigeria are Associated with Multidrug Resistant Atypical El Tor and non-O1/non-O139 Vibrio cholerae., M. A. Marin, Cristiane C. Thompson, F. S. Freitas, E. L. Fonseca, and Iruka N. Okeke

SMG-ly Knocking out Gene Expression in Specific Cells; An Educational Primer, Philip M. Meneely and J. C. Bloom

Kuby Immunology, Judith A. Owen, Jennifer Punt, Sharon A. Stranford, and Patricia P. Jones


Exploring the Interactions between a Coiled-Coil Model Peptide System and Metallated Porphyrins towards the Design of Photoelectronically active Biomaterials, James C. Taggart '13, Elizabeth Z. Welch, Bashkim Kokona, and Robert Fairman


Modeling 400 million years of plant hydraulics, Jonathan P. Wilson

Submissions from 2012

Prolonged febrile illness due to CTX-M-15 extended spectrum beta-lactamase-producing Klebsiella pneumoniae infection in Nigeria, Aaron O. Aboderin, O. Adefehinti, B. W. Odetoyin, and Iruka N. Okeke

NF-Y is necessary for hematopoietic stem cell proliferation and survival, Gerd Bungartz, Hannah Land, David T. Scadden, and Stephen G. Emerson

Effect of charged residue side chain length on intrahelical glutamate-lysine ion pairing interactions, Richard P. Cheng, Wei-Ren Wang, Prashant Girinath, and Robert Fairman

Evolutionary Voyage of Angiosperm Vessel Structure-Function and its Significance for Early Angiosperm Success, T. S. Field and Jonathan P. Wilson

NR4A1 (Nur77) Deletion Polarizes Macrophages Toward an Inflammatory Phenotype and Increases Atherosclerosis, Richard N. Hanna, Iftach Shaked, Harper G. Hubbeling, and Jennifer Punt


Regional Dissemination of a Trimethoprim-Resistance Gene Cassette via a Successful Transposable Element, Amy S. Labar '10, Jennifer S. Millman '09, E. Ruebrush, and Iruka N. Okeke


Netrin/DCC signaling guides olfactory sensory axons to their correct location in the olfactory bulb, Vanisha Lakhina, Christina L. Marcaccio, Xin Shao, and Roshan A. Jain

Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses, Justine Melo

Crossover distribution and frequency are regulated by him-5 in Caenorhabditis elegans, Philip M. Meneely, Olivia L. McGovern, Frazer I. Heinis, and Judith L. Yanowitz


Africa in the time of cholera: a history of pandemics from 1817 to the present [book review], Iruka N. Okeke

Measures to ensure better use of antibiotics, Iruka N. Okeke


Actin polymerization controls the activation of multidrug efflux at fertilization by translocation and fine-scale positioning of ABCB1 on microvilli., Kristen E. Whalen, A Reitzel, and A. Hamdoun

Deep-Water Incised Valley Deposits at the Ediacaran-Cambrian Boundary in Southern Namibia Contain Abundant Treptichnus Pedum, Jonathan P. Wilson, J. P. Grotzinger, Wooward W. Fischer, and K. P. Hand

Submissions from 2011

Enteroaggregative E. coli O104 from an outbreak of HUS in Germany 2011, could it happen again?, Marie Anne Chattaway, Tim Dallman, Iruka N. Okeke, and John Wain

GSK3-mediated instability of tubulin polymers is responsible for the failure of immature CD4+CD8+thymocytes to polarize their MTOC in response to TCR stimulation, Nicole R. Cunningham, Emily M. Hinchcliff '08, Vassily I. Kutyavin '11, and Jennifer Punt

The Vaccinia Virus A56 protein: A Multifunctional Transmembrane Glycoprotein that Anchors Two Secreted Viral Proteins, Brian DeHaven


Measuring oscillatory velocity fields due to swimming algae, J. S. Guasto, Karl A. Johnson, and Jerry P. Gollub

The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C(-) monocytes, Richard N. Hanna, Leo M. Carlin, Harper G. Hubbeling, and Jennifer Punt

A Phase 1 Dose Escalation Study of Infusion of Ex Vivo CD3/CD28 Costimulated Umbilical Cord Blood-Derived T Cells in Adults Undergoing Transplanation for Advanced Hematologic Malignancies , E. O. Hexner, S. M. Luger, J. K. Mangan, and Stephen G. Emerson

How the Hox Gene Ubx Specifies Two Different Segment Identities, Rachel E. Hoang

Hox Genes And The Evolution Of The Vertebrate Body Plan, Rachel E. Hoang

Interactions Between Vertebrate Hox Genes, Rachel E. Hoang

The Dynamics and Mechanics of Apical Constriction, Rachel E. Hoang


Molecular-genetic mapping of zebrafish mutants with variable phenotypic penetrance, Roshan A. Jain, Marc A. Wolman, and Lauren A. Schmidt

Enhancement of biomixing by swimming algal cells in two-dimensional films, H. Kurtuldu, J. S. Guasto, Karl A. Johnson, and Jerry P. Gollub


Rapid evolution of fluoroquinolone-resistant Escherichia coli in Nigeria is temporally associated with fluoroquinolone use, Adebayo Lamikanra, Jennifer L. Crowe, Rebeccah S. Lijek '07, and Iruka N. Okeke

A novel Nr4a1(GFP) Reporter System Reveals that Nr4a1 Expression Identifies Long-Term Hematopoietic Stem Cells, Ruben Land '12, Trevor Barlowe '13, Shwetha Manjunath '11, Stephen G. Emerson, and Jennifer Punt

The Heat-Resistant Agglutinin Family Includes a Novel Adhesin from Enteroaggregative Escherichia coli Strain 60A, Justin Mancini '09, Brooke Weckselblatt, Yoonjie K. Chung '10, and Iruka N. Okeke


T cell receptor signal strength in Treg and iNKT cell development as revealed by a novel fluorescent reporter mouse, Amy E. Moran, Keli L. Holzapfel, Nicole R. Cunningham, and Jennifer Punt

Non-prescription antimicrobial use worldwide: a systematic review, D. J. Morgan, Iruka N. Okeke, R. Laxminarayan, and E. N. Perencevich


Quinolone resistance in Escherichia coli from Accra, Ghana, Sreela S. Namboodiri '08, Japheth A. Opintan, Rebeccah S. Lijek '07, and Iruka N. Okeke

Biomedical Loopholes, Distrusted State and the Politics of HIV/AIDS 'Cure' in Nigeria, E. B. Obadare and Iruka N. Okeke

Divining without seeds : the case for strengthening laboratory medicine in Africa, Iruka N. Okeke

Ensuring Global Access to Quality Medicines: Role of the US Pharmacopeia, Iruka N. Okeke, Matthew L. Heyman, and Roger L. Williams


IS3 Profiling Identifies the Enterohaemorrhagic Escherichia Coli O-island 62 in a Distinct Enteroaggregative E. Coli Lineage, Iruka N. Okeke, Louissa R. MacFarlane-Smith, Jonathan N. Fletcher, and Anna M. Snelling

Diagnostics as Essential Tools for Antimicrobial Resistance Containment, Iruka N. Okeke, Rosanna W. Peeling, Herman Goossens, and Raymond Auckenthaler