Submissions from 2018
Drosophila Insulin receptor regulates the persistence of injury-induced nociceptive sensitization, Seol Hee Im, Atit A. Patel, Daniel N. Cox, and Michael J. Galko
A Forward Genetic Screen in Zebrafish Identifies the G-protein coupled receptor CaSR as a modulator of Sensorimotor Decision-making, Roshan A. Jain, Christina Szi '18, Amy Zamora '18, Keisuke Sawada '17, and Emilia Cobbs '17
A Cyfip2-Dependent Excitatory Interneuron Pathway Establishes the Innate Startle Threshold, Kurt C. Marsden, Roshan A. Jain, Marc A. Wolman, Ben Miltenberg '17, and Alberto E. Pereda
Structure, function, and control of the human musculoskeletal network, Andrew Murphy, Sarah Muldoon, David Baker, Adam Lastowka, Brittany Bennett, Muzhi Yang, and Danielle Bassett
Aggregative Adherence and Intestinal Colonization by Enteroaggregative Escherichia coli Are Produced by Interactions among Multiple Surface Factors, Iruka N. Okeke, Laura V. Blanton, Lawrence T. Wang, Jennifer Hofmann, Joshua DuBow '11, Alexander Lafrance '16, Stephen Kwak '12, Levi Bowers '17, Mandara C. Levine '18, Charles O. Hale '17, and Philip Meneely
Submissions from 2017
Hominids adapted to metabolize ethanol long before human-directed fermentation, Mathew Carrigan
Twists And Turns In Protein Assembly, Robert Fairman
Uncovering Protein-Protein Interactions through a Team-based Undergraduate Biochemistry Course, Robert Fairman, D. L. Cookmeyer, S. E. Winesett, and B. Kokona
Sedimentation velocity analysis with fluorescence detection of mutant huntingtin exon 1 aggregation in Drosophila Melanogaster and Caenorhabditis Elegans, Robert Fairman, Surin Kim '15, Victoria D'Acunto '17, Jay Garcia '16, Nabeel Akhtar '13, Susanna Hoffman '14, Seema Doshi '16, and Kathleen Ulrich '18
Genetics: Genes, genomes, and evolution, Kate Heston, Rachel Hoang, Philip Meneely, and Iruka Okeke
Submissions from 2016
Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO, Hande Boyanci, Tayyab Shah, Amanda Hurley, and Robert Fairman
Studying polyglutamine aggregation in Caenorhabditis elegans using an analytical ultracentrifuge equipped with fluorescence detection, Robert Fairman, Lynn Richmond '13, Jay Garcia '16, and Kathleen Ulrich '14
Weak tradeoff between xylem safety and xylem-specific hydraulic efficiency across the world's woody plant species, Sean M. Gleason, Mark Westoby, Steven Jansen, and Radika Bhaskar
A Bacterial Quorum-Sensing Precursor Induces Mortality in the Marine Coccolithophore, Emiliania huxleyi, E. L. Harvey, R. W. Deering, D. C. Rowley, and Kristen E. Whalen
Estrogens Suppress a Behavioral Phenotype in Zebrafish Mutants of the Autism Risk Gene, CNTNAP2, Ellen J. Hoffman, Katherine J. Turner, Joseph M. Fernandez, and Roshan A. Jain
Probing the selectivity of beta-hydroxylation reactions in non-ribosomal peptide synthesis using analytical ultracentrifugation, Bashkim Kokona, Emily S. Winesett '16, A. Nikolai von Krusenstiern '15, Robert Fairman, and Louise K. Charkoudian
Was atmospheric CO2 capped at 1000 ppm over the past 300 million years?, Jennifer C. McElwain, Isabel P. Montañez, Joseph D. White, and Jonathan P. Wilson
Pick Your Poisson: An Educational Primer for Luria and Delbruck's Classic Paper, Philip Meneely
Climate, p(CO2) and terrestrial carbon cycle linkages during late Palaeozoic glacial-interglacial cycles, Isabel P. Montanez, Jennifer C. McElwain, Christopher J. Poulsen, and Jonathan P. Wilson
Diarrhoeagenic Escherichia coli in mother-child Pairs in Ile-Ife, South Western Nigeria, Iruka N. Okeke, Babatunde W. Odetoyin, Jennifer Hofmann, and Aaron O. Aboderin
Biosynthesis of coral settlement cue tertrabromopyrrole in marine bacteria by a uniquely adapted brominase-thiosterase enzyme pair., Kristen E. Whalen, Abrahim El Gamal, Vinayak Agarwal, and Stefan Diethelm
Hydraulics of Psilophyton and evolutionary trends in plant water transport after terrestrialization, Jonathan P. Wilson
Submissions from 2015
Effect of Helix Length on the Stability of the Lac Repressor Antiparallel Coiled Coil, Wheaton Little, James P. Robblee, Caroline L. Dahlberg, Bashkim Kokona, and Robert Fairman
Enhancement of antibiotic activity against multidrug resistant bacteria by efflux pump inhibitor, 3,4‐dibromo‐2,5‐dione, isolated from a Pseudoalteromonas sp, Kristen E. Whalen, K. L. Poulson, R. W. Deering, and D. C. Rowley
A genome-wide screen identifies PAPP-AA-mediated IGFR signaling as a novel regulator of habituation learning, Marc A. Wolman, Roshan A. Jain, and Kurt C. Marsden
Submissions from 2014
Enteroaggregative Escherichia coli Have Evolved Independently as Distinct Complexes within the E-coli Population with Varying Ability to Cause Disease, Marie Anne Chattaway, Claire Jenkins, Dunstan Rajendram, and Iruka N. Okeke
Comparative Genomics of 274 Vibrio Cholerae Genomes Reveals Mobile Functions Structuring Three Niche Dimensions, Bas E. Dutilh, Cristiane C. Thompson, Ana C P Vicente, and Iruka N. Okeke
Effect of Helical Flanking Sequences on the Morphology of Polyglutamine-Containing Fibrils, Bashkim Kokona, Karl A. Johnson, and Robert Fairman
Role of the Coiled-Coil Structural Motif in Polyglutamine Aggregation, Bashkim Kokona, Zachary P. Rosenthal, and Robert Fairman
Genetic Analysis: Genes, Genomes, and Networks in Eukaryotes, 2nd edition, Philip Meneely
Diagnostic Schemes for Reducing Epidemic Size of African Viral Hemorrhagic Fever Outbreaks, Iruka N. Okeke and Robert S. Manning
Confronting Contagion: Our Evolving Understanding of Disease, Melvin Santer
Dissemination of the Transmissible Quinolone-Resistance Gene qnrS1 by IncX Plasmids in Nigeria, Eric T. Sumrall '13, Elizabeth B. Gallo '12, Aaron Aboderin Oladipo, Adebayo Lamikanra, and Iruka N. Okeke
Testing the Role of Charge and Structure on the Stability of Peptide-Porphyrin Complexes, James C. Taggart, Elizabeth Z. Welch, Mary F. Mulqueen, Vincent B. Dioguardi, and Robert Fairman
Submissions from 2013
The Carbon Isotope Organic Geochemistry of Early Ordovician Rocks from the Annascaul Formation, County Kerry, A. H. Jahren, Brian A. Schubert, Leszek Marynowski, and Jonathan P. Wilson
Using a Peptide System to test the Coiled-Coil Model of Polyglutamine Aggregation, Bashkim Kokona, Karl A. Johnson, and Robert Fairman
Flagellar Waveform Dynamics of Freely Swimming Algal Cells, H. Kurtuldu, D. Tam, A. E. Hosoi, and Karl A. Johnson
Cholera Outbreaks in Nigeria are Associated with Multidrug Resistant Atypical El Tor and non-O1/non-O139 Vibrio cholerae., M. A. Marin, C. C. Thompson, F. S. Freitas, E. L. Fonseca, and Iruka N. Okeke
SMG-ly Knocking out Gene Expression in Specific Cells; An Educational Primer, Philip M. Meneely and J. C. Bloom
Kuby Immunology, Judith A. Owen, Jennifer Punt, Sharon A. Stranford, and Patricia P. Jones
Exploring the Interactions between a Coiled-Coil Model Peptide System and Metallated Porphyrins towards the Design of Photoelectronically active Biomaterials, James C. Taggart '13, Elizabeth Z. Welch, Bashkim Kokona, and Robert Fairman
Modeling 400 million years of plant hydraulics, Jonathan P. Wilson
Submissions from 2012
Prolonged febrile illness due to CTX-M-15 extended spectrum beta-lactamase-producing Klebsiella pneumoniae infection in Nigeria, A. O. Aboderin, O. Adefehinti, B. W. Odetoyin, and Iruka N. Okeke
NF-Y is necessary for hematopoietic stem cell proliferation and survival, Gerd Bungartz, Hannah Land, David T. Scadden, and Stephen G. Emerson
Effect of charged residue side chain length on intrahelical glutamate-lysine ion pairing interactions, Richard P. Cheng, Wei-Ren Wang, Prashant Girinath, and Robert Fairman
Evolutionary Voyage of Angiosperm Vessel Structure-Function and its Significance for Early Angiosperm Success, T. S. Field and Jonathan P. Wilson
NR4A1 (Nur77) Deletion Polarizes Macrophages Toward an Inflammatory Phenotype and Increases Atherosclerosis, Richard N. Hanna, Iftach Shaked, Harper G. Hubbeling, and Jennifer Punt
Regional Dissemination of a Trimethoprim-Resistance Gene Cassette via a Successful Transposable Element, Amy S. Labar '10, Jennifer S. Millman '09, E. Ruebrush, and Iruka N. Okeke
Netrin/DCC signaling guides olfactory sensory axons to their correct location in the olfactory bulb, Vanisha Lakhina, Christina L. Marcaccio, Xin Shao, and Roshan A. Jain
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses, Justine Melo
Crossover distribution and frequency are regulated by him-5 in Caenorhabditis elegans, Philip M. Meneely, Olivia L. McGovern, Frazer I. Heinis, and Judith L. Yanowitz
Africa in the time of cholera: a history of pandemics from 1817 to the present [book review], Iruka N. Okeke
Measures to ensure better use of antibiotics, Iruka N. Okeke
Actin polymerization controls the activation of multidrug efflux at fertilization by translocation and fine-scale positioning of ABCB1 on microvilli., Kristen E. Whalen, A Reitzel, and A. Hamdoun
Deep-Water Incised Valley Deposits at the Ediacaran-Cambrian Boundary in Southern Namibia Contain Abundant Treptichnus Pedum, Jonathan P. Wilson, J. P. Grotzinger, Wooward W. Fischer, and K. P. Hand
Submissions from 2011
Evolution of folded gastrulation: A comparison between Drosophila melanogaster and Drosophila pseudoobscura, Frederick Arnold '12, Kimberly Dao '09, Jill Geratowski '11, and Rachel E. Hoang
Enteroaggregative E. coli O104 from an outbreak of HUS in Germany 2011, could it happen again?, Marie Anne Chattaway, Tim Dallman, Iruka N. Okeke, and John Wain
GSK3-mediated instability of tubulin polymers is responsible for the failure of immature CD4+CD8+thymocytes to polarize their MTOC in response to TCR stimulation, Nicole R. Cunningham, Emily M. Hinchcliff '08, Vassily I. Kutyavin '11, and Jennifer Punt
The Vaccinia Virus A56 protein: A Multifunctional Transmembrane Glycoprotein that Anchors Two Secreted Viral Proteins, Brian DeHaven
Measuring oscillatory velocity fields due to swimming algae, J. S. Guasto, Karl A. Johnson, and Jerry P. Gollub
The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C(-) monocytes, Richard N. Hanna, Leo M. Carlin, Harper G. Hubbeling, and Jennifer Punt
A Phase 1 Dose Escalation Study of Infusion of Ex Vivo CD3/CD28 Costimulated Umbilical Cord Blood-Derived T Cells in Adults Undergoing Transplanation for Advanced Hematologic Malignancies , E. Hexner, S. M. Luger, J. K. Mangan, and Stephen G. Emerson
How the Hox Gene Ubx Specifies Two Different Segment Identities, Rachel E. Hoang
Hox Genes And The Evolution Of The Vertebrate Body Plan, Rachel E. Hoang
Interactions Between Vertebrate Hox Genes, Rachel E. Hoang
The Dynamics and Mechanics of Apical Constriction, Rachel E. Hoang
Molecular-genetic mapping of zebrafish mutants with variable phenotypic penetrance, Roshan A. Jain, Marc A. Wolman, and Lauren A. Schmidt
Enhancement of biomixing by swimming algal cells in two-dimensional films, H. Kurtuldu, J. S. Guasto, Karl A. Johnson, and Jerry P. Gollub
Rapid evolution of fluoroquinolone-resistant Escherichia coli in Nigeria is temporally associated with fluoroquinolone use, Adebayo Lamikanra, Jennifer L. Crowe, Rebeccah S. Lijek '07, and Iruka N. Okeke
A novel Nr4a1(GFP) Reporter System Reveals that Nr4a1 Expression Identifies Long-Term Hematopoietic Stem Cells, Ruben Land '12, Trevor Barlowe '13, Shwetha Manjunath '11, Stephen G. Emerson, and Jennifer Punt
The Heat-Resistant Agglutinin Family Includes a Novel Adhesin from Enteroaggregative Escherichia coli Strain 60A, Justin Mancini '09, Brooke Weckselblatt, Yoonjie K. Chung '10, and Iruka N. Okeke
T cell receptor signal strength in Treg and iNKT cell development as revealed by a novel fluorescent reporter mouse, Amy E. Moran, Keli L. Holzapfel, Nicole R. Cunningham, and Jennifer Punt
Non-prescription antimicrobial use worldwide: a systematic review, D. J. Morgan, Iruka N. Okeke, R. Laxminarayan, and E. N. Perencevich
Quinolone resistance in Escherichia coli from Accra, Ghana, Sreela S. Namboodiri '08, Japheth A. Opintan, Rebeccah S. Lijek '07, and Iruka N. Okeke
Biomedical Loopholes, Distrusted State and the Politics of HIV/AIDS 'Cure' in Nigeria, E. B. Obadare and Iruka N. Okeke
Divining without seeds : the case for strengthening laboratory medicine in Africa, Iruka N. Okeke
Ensuring Global Access to Quality Medicines: Role of the US Pharmacopeia, Iruka N. Okeke, Matthew L. Heyman, and Roger L. Williams
IS3 Profiling Identifies the Enterohaemorrhagic Escherichia Coli O-island 62 in a Distinct Enteroaggregative E. Coli Lineage, Iruka N. Okeke, Louissa R. MacFarlane-Smith, Jonathan N. Fletcher, and Anna M. Snelling
Diagnostics as Essential Tools for Antimicrobial Resistance Containment, Iruka N. Okeke, Rosanna W. Peeling, Herman Goossens, and Raymond Auckenthaler
Characterization of Mesoscale Coiled-Coil Peptide-Porphyrin Complexes, Brian J. Pepe-Mooney '10, Bashkim Kokona, and Robert Fairman
IFNs Upregulate Sca-1 and Block Proliferation in Murine Hematopoietic Stem and Progenitor Cells, K. Shank, Y. Shin, C. Wills, and Jennifer Punt
A late phase of germ plasm accumulation during Drosophila oogenesis requires lost and rumpelstiltskin, Kristina S. Sinsimer, Roshan A. Jain, Seema Chatterjee, and Elizabeth R. Gavis
Vibrio cholerae O1 lineages driving cholera outbreaks during seventh cholera pandemic in Ghana, Cristiane C. Thompson, F. S. Freitas, Michel A. Marin, and Iruka N. Okeke
Drug-resistant Bacteria and Childhood Diarrhea in Africa, Faith Wallace-Gadsden and Iruka N. Okeke
Geochemical Support for a Climbing Habit within the Paleozoic Seed Fern Genus Medullosa, Jonathan P. Wilson and Woodward W. Fischer
Hydraulics of Asteroxylon mackei, an early Devonian vascular plant, and the early evolution of water transport tissue in terrestrial plants, Jonathan P. Wilson and Woodward W. Fischer
Chemical modulation of memory formation in larval zebrafish, Marc A. Wolman, Roshan A. Jain, Laura Liss, and Michael Granato
Notch signaling is a critical regulator of allogeneic CD4(+) T-cell responses mediating graft-versus-host disease, Yi Zhang, Ashley R. Sandy, Jina Wang, and Stephen G. Emerson
Submissions from 2010
Positional Effects on Helical Ala-Based Peptides, Richard P. Cheng, Prashant Girinath, Yuta Suzuki, and Robert Fairman
Molecular Biology: Principles of Genome Function, Nancy L. Craig, Orna Cohen-Fix, Rachel Green, and Philip M. Meneely
TAT-mediated transduction of NF-Ya peptide induces the ex vivo proliferation and engraftment potential of human hematopoietic progenitor cells, Alevtina D. Domashenko, Gwenn Danet-Desnoyers, Alissa Aron '11, and Stephen G. Emerson
Pharmacologic eigenvalues: beating the rap on bone marrow failure, Stephen G. Emerson and R. W. Garrett
The Vaccinia Virus Complement Control Protein Modulates Adaptive Immune Responses during Infection, N. M. Girgis and Brian DeHaven
Xenopus sonic hedgehog Guides Retinal Axons Along the Optic Tract, Laura Gordon, Matthew Mansh, Helen Kinsman, and Andrea R. Morris
Oscillatory Flows Induced by Microorganisms Swimming in Two Dimensions, J. S. Guasto, Karl A. Johnson, and Jerry P. Gollub
Journal Club, Rachel E. Hoang
A Pathoadaptive Deletion in an Enteroaggregative Escherichia coli Outbreak Strain Enhances Virulence in a Caenorhabditis elegans Model, Jennifer Hwang '09, Lisa M. Mattei, Laura G. Van Arendonk '10, Philip M. Meneely, and Iruka N. Okeke
The Effects of Mild Post-Stroke Exercise on Reactive Neurogenesis and Recovery of Somatosensation in Aged Rats, J. L. Leasure and Michael Grider